Isotretinoin, also known as 13-cis-retinoic acid and sold under the brand name Accutane among others, is a medication used to treat skin diseases like harlequin-type ichthyosis, lamellar ichthyosis, and severe cystic acne or moderate acne that is unresponsive to antibiotics. [5] What is Accutane? Accutane is a form of vitamin A. It reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly. Accutane is used to treat severe nodular acne that has not responded to other treatments, including antibiotics. Accutane® (Isotretinoin) is a type of retinoid medication that treats severe acne. A healthcare provider may prescribe this medication if other acne medications don’t work. Accutane (Isotretinoin) may treat acne, warnings, side effects, dosage, drug interactions, patient labeling, reviews, and related medications including drug comparison and health resources. Isotretinoin is used to treat severe, disfiguring nodular acne. It should be used only after other acne medicines or antibiotics have been tried and have failed to help the acne. Isotretinoin may also be used to treat other skin diseases as determined by your doctor. What Is Accutane and Why Is It Prescribed? Accutane was the brand name for isotretinoin, a prescription medicine for people with any type of acne, including cystic, nodular or severe acne that other treatments couldn’t manage. Roche manufactured Accutane but discontinued it in 2009. The iPLEDGE REMS is a safety program to manage the risk of isotretinoin’s teratogenicity and to minimize fetal exposure. The REMS is required by the U.S. Food and Drug Administration (FDA) to ensure the benefits of isotretinoin outweigh its risks. What It Is: Isotretinoin, often known by its brand name Accutane ®, is an oral medication approved for severe, scarring acne that is normally prescribed for 15-20 weeks. Accutane package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology. Overview: Isotretinoin is used to treat acne. It reduces oil on your skin and changes how your skin cells grow and shed so they do not clog pores or form acne. Common side effects may include.